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The quote that would secure Jim Mattis’ reputation as the most celebrated Marine general of his generation came during meetings he hadn’t wanted to attend. It was April 2004, a half-mile east of the Iraqi city of Fallujah, which had exploded in an insurrection that threatened to doom the American occupation after barely a year. Mattis hadn’t wanted to take Fallujah, recognizing that flattening the City of Mosques would throw gasoline on a smoldering nationwide insurrection. But he followed White House-pushed orders to invade, and after roughly a week...

“I believed in her,” chemist Ian Gibbons (Stephen Fry) says of tech mogul Elizabeth Holmes (Amanda Seyfried) midway through the Hulu docudrama The Dropout. “I looked in her eyes and I thought… I thought I could see the future.”

Ian is far from the only person to believe this of Holmes, whose company, Theranos, promised to revolutionize health care with a device, the Edison, that would run multiple tests from a single drop of blood. The cult of personality around the black-clad young woman helped attract heavyweights like former secretary...

The Hulu series “The Dropout,” which will tell the story of Theranos founder Elizabeth Holmes, has locked in an impressive lineup of guest stars.

William H. Macy, Laurie Metcalf, Elizabeth Marvel, Utkarsh Ambudkar, Kate Burton, Stephen Fry, Michel Gill, Michael Ironside, Bill Irwin, and Josh Pais have all joined the show. They will appear alongside series lead Amanda Seyfried, who will play Holmes, and Naveen Andrews, who will play Sunny Balwani.

Macy will play Richard Fuisz, an ex-CIA agent and an inventor of biomedical devices. A friend of the Holmes family, he is initially upset when he learns that Elizabeth has started a medical tech startup without consulting him, and his resentment and obsession will have serious ramifications for Elizabeth and Theranos.

Macy is repped by ICM Partners.

Metcalf will play Phyllis Gardner, a scientist, doctor and successful entrepreneur. As a woman in a predominately male world, she has...

Hulu has set a stellar recurring cast for The Dropout, its upcoming limited series about the rise and fall of Elizabeth Holmes and her company, Theranos. William H. Macy, Laurie Metcalf, Elizabeth Marvel, Utkarsh Ambudkar, Kate Burton, Stephen Fry, Michel Gill, Michael Ironside, Bill Irwin and Josh Pais join Amanda Seyfried in the series from Liz Meriwether, Seachlight Television and Disney Television Studios’ 20th Television. Production is scheduled to begin this summer.

Created and executive produced by Meriwether, who also serves as showrunner, The Dropout is based on the ABC News/ABC Radio podcast. Holmes (Seyfried), the enigmatic Stanford dropout who founded medical testing start-up Theranos, was lauded as a Steve Jobs for the next tech generation. Once worth billions of dollars, the myth crumbled when it was revealed that none of the tech actually worked, putting thousands of people’s health in grave danger. Money. Romance. Tragedy. Deception. The...