- Heavily influenced by fellow North Carolina musician Doc Watson. Avett met Doc as a thirteen-year-old when he was invited to Doc's home before one of his shows in Winston-Salem. The experience had a profound impact on Seth's life, and he later wrote about it in an article published in Garden and Gun Magazine after Doc's death.
- In addition to his band The Avett Brothers, he has released three solo records under the moniker Timothy Seth Avett as Darling.
- Has a notoriously good relationship with his brother and band mate, Scott Avett. Has stated that Scott is his best friend.
- Is a fan of hip-hop music. Counts the album "Shadows on the Sun" by hip-hop artist Brother Ali to be one of his top ten favorite albums of all time.
- Is the youngest of three children.
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