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Warning: This article contains spoilers for Grey's Anatomy season 21, episode 8, "Drop It Like It's Hot."

Grey's Anatomy fans are experiencing an upheaval with the happier exit of Levi Schmitt (Jake Borelli) and the tragic one of Mika Ysauda (Midori Francis) happening back to back. The latter may now be one of Grey's Anatomy's saddest exits, as Mika decides that she can no longer work at Grey Sloan as it is haunted by Chloe (Julia Rose), her sister who was killed in a horrific car crash. After her own recovery, attempting to return to work, and having a terrible, enlightening day, Mika breaks up with Jules (Adelaide Kane) and walks out the hospital's doors for good.

Grey's Anatomy is notorious for heartrending character deaths, the most common way to write a character out of the show in the early seasons, but it has become rarer in recent years.

[This story contains spoilers from Grey’s Anatomy season 21, episode eight, “Drop It Like It’s Hot.”]

Grey’s Anatomy had said farewell to another series regular.

Midori Francis’ surgical intern Mika Yasuda scrubbed in to Seattle’s Grey Sloan Memorial Hospital for the last time on Thursday, after joining the show at the start of season 19.

The eighth episode of season 21 — also the fall finale of the hit ABC medical drama, which returns March 6, 2025 — picked up after Jake Borelli’s Dr. Levi Schmitt also departed Grey’s Anatomy. Yasuda’s younger sister, Chloe (Julia Rose Gruenberg), tragically died after a horrible car accident when Yasuda fell asleep at the wheel after pulling an all-nighter at the hospital. The combination of Chloe’s wounds from the accident and the impact of chemo on her body from treating her cancer proved to be fatal, and Chloe died from her injuries.

At the start of this week’s episode,...

Note: The following story contains spoilers from “Grey’s Anatomy” Season 21, Episode 8.

“Grey’s Anatomy” lost a major cast member during its Season 21 fall finale, and left another one in grave danger ahead of a long winter break.

Episode 8, titled “Drop It Like It’s Hot,” saw a grief-stricken Mika Yasuda (Midori Francis) returned to work after the death of her younger sister in the previous episode. They had both been involved in a car accident when Mika fell asleep at the wheel. In the end, the guilt she had over her sister’s death was not enough for Mika to stick around and continue her job as a surgical intern. She had packed her locker and said goodbye for good by the end of the eventful hour.

And she left plenty of heartbreak in her wake. Mika struggled during a code blue situation with Dr. Miranda Bailey (Chandra Wilson), when she...

Note: This story contains spoilers from “Grey’s Anatomy” Season 21, Episode 6.

“Grey’s Anatomy” began saying goodbye to Dr. Levi Schmitt in this week’s episode — while teasing a potential tragic ending for Dr. Mika Yasuda.

Fans have expected to bid farewell to cast members Jake Borelli and Midori Francis, who play Drs. Schmitt and Yasuda, respectively, since reports surfaced earlier this year that both would exit the ABC medical drama sometime in Season 21. While both actors have taken part in substantial storylines this season so far, Thursday’s hour solidified one of the goodbyes as a potential happy ending, while the other doctor might not make it out alive.

Episode 6, titled “Night Moves,” followed as the Grey Sloan Memorial hospital doctors did their typical juggling of tense medical cases with personal troubles. As he considered a medical research opportunity in Texas, Levi spent the hour being wooed by Dr. Miranda Bailey (Chandra Wilson) and Dr.

Just as we got a relationship that we could get behind, Grey’s Anatomy has thrown us a curveball. What can we expect in Grey’s Anatomy season 21, episode 4?

Now, let’s be honest, we knew that Midori Francis was leaving the series. That meant we weren’t really sold on the Mika/Jules romance. That didn’t mean we don’t want or need it, but when you announce a character is leaving, we rule out personal connections lasting.

Now it looks like we have that exit storyline. Here’s what we can expect.

It’s all about Mika’s little sister in Grey’s Anatomy season 21, episode 4

At the end of the previous episode, Mika shared with Jules that her sister had been diagnosed with rectal cancer. It’s time to find out how bad that is, especially considering she is only 22. The promo makes it clear that things aren’t looking great,...

Sophia Bush is scrubbing into Grey’s Anatomy! Find out who she’s playing in the hit drama here!

Grey’s Anatomy has a great habit of bringing in some good actors for recurring roles that often turn into regulars. Last season, Natalie Morales joined the show as Dr. Monica Beltran, who’s now a regular face. The Season 21 premiere brought back Dr. Sydney Heron (Kali Rocha), who hadn’t been seen since Season 7. Her return was short-lived, as the latest episode had Heron departing when Bailey took back her job.

Grey’s will undergo a cast shift soon as Midori Francis will soon be departing as intern Mika Yasuda. An upcoming episode introduces Mika’s sister Chloe (Julia Rose), who checks in as a patient, and this could be a plotline to write off the character.

It’s fun seeing some actors pop in for roles meant to be short, only...

Even after its landmark twentieth season, Shonda Rhimes’ Grey’s Anatomy already has a Season 21 in the works. Even with Ellen Pompeo’s big sendoff in the 2023 midseason premiere of the show, she has continued to appear in the following seasons.

The Shonda Rhimes’ procedural drama series debuted on March 27, 2005 on ABC, and the show continues to draw audiences well into almost 20 years of its run. Those curious about the 21st season of the medical show can read everything we know below.

When will Season 21 of Grey’s Anatomy come out?

Season 21 arrives September 26 at 10 p.m. on ABC. The show’s renewal came about in April 2024.

How many episodes will be in Season 21 of Grey’s Anatomy?

Deadline hears that the expectation is 18 episodes, compared to the 10-episode 20th season, which was impacted by the double strike in Hollywood in 2023.

Will Ellen Pompeo come back for Season 21 of Grey’s Anatomy?

Yes, Ellen...

The beginning of the end is here for Mika Yasuda. It was revealed in Season 20 that Midori Francis would leave Grey's Anatomy in Season 21 alongside Jake Borelli. There was no information on how or when the character would leave, but given the recent developments in her personal life, the end might be near for her. Deadline revealed that Julia Rose was cast as Chloe Yasuda, Mika's younger sister who visits Grey Sloan for treatment. In Grey's Anatomy Season 21 Episode 3, Mika learns that her sister has been diagnosed with a rare cancer. The promo and logline for Episode 4, "This One's for the Girls," below tease this arc, Ben's return to the hospital, Jo and Link's relationship, and Levi's potential romance with the chaplain.

Exclusive: We will get to know a little more about Mika Yasuda’s (Midori Francis) personal life before she leaves Grey Sloan Memorial Hospital. Julia Rose (Baskets) has been cast in a recurring role as Mika’s sister, Chloe Yasuda. She will be introduced in Episode 2104 and will appear in four episodes.

Witty with a great sense of humor, Chloe Yasuda (Rose), who has been admitted to Grey Sloan as a patient, is a harried honor student and VP of student activities who also runs varsity cross-country at her college. You can see above and below exclusive first-look images of Chloe’s reunion with her sister and introduction to the rest of the interns.

Chloe is the first Yasuda family member to be introduced on Grey’s Anatomy. She is one of eight siblings and seven sisters Mika has revealed she has.

As Deadline reported in May, Francis is one of two Grey’s Anatomy series regulars,...