Florence Foster Jenkins created all her own outfits, inspired by the style of "a Mexican señorita" and 18th-century ball gowns. She also designed her pair of heavenly wings. According to costume designer Consolata Boyle, "She was a supreme performer, so her clothes were gorgeously outrageous. They were high camp but with a softness so she drew people in. And she had no embarrassment about how she looked."
Hugh Grant had semi-retired when director Stephen Frears convinced him to star in this film. Grant said he participated in the film to act opposite Meryl Streep.
Meryl Streep said of co-starring with Hugh Grant as her romantic partner; "I always thought I was too old. But he got older".
Florence Foster Jenkins was in an accident while in a taxi. She was unharmed, but gave the taxi driver a box of cigars because she could now hit a higher note than she could before the accident.