Jamie Chung auditioned for the role of Psylocke which went to Mei Melançon in X-Men: The Last Stand (2006) and Olivia Munn in X-Men: Apocalypse (2016).
In the comics Andreas and Andrea Von Strucker are the children of HYDRA Leader Baron Von Strucker who made an appearance in Captain America: The Winter Soldier (2014) and Avengers: Age of Ultron (2015).
Each episode in Season 1 has a capital X in its title and Season 2 has a capital M in its title. This is meant to reference "X-Men". It's possible that had the show continued for two more seasons, all Season 3 titles would have had a capital E in them and all Season 4 titles a capital N.
Polaris was slightly redesigned closer to Emma Dumont's appearance in this series when the character starred in "X-Men Blue" which was being published at the same time Season One aired.
This is the sixth "X-Men" TV series, but only the second one to be in live-action.