Trace Beaulieu voices the robot A.R.T. He also voiced the character of Crow on Mystery Science Theater 3000, who was referred to as Art by the character Pearl Forrester.
Both Karan Soni and Milana Vayntrub are frequent characters in AT&T commercials.
Milana Vayntrub and Conor Leslie both play superheroes in TV shows based on characters from competing comic publishers. Vayntrub voiced Squirrel Girl (Doreen Green) in four animated Marvel Comics shorts called Marvel Rising in 2018 and 2019. She is also scheduled to play that character in the live action New Warriors when it is produced. Leslie plays Wonder Girl (Donna Troy) in the DC Comics series Titans (2018).
Featured in an April 6th, 2015 article in The New Yorker magazine called "The Nerd Hunter" about casting director Allison Jones.
The first season of premiered on April 14, 2015. The series was not renewed for a second season due to Yahoo! Screen being shut down the following year. The rights for Other Space were later picked up by DUST, which took over hosting duties for the series in 2020.