Live version was remixed to remove the live audience and was released as a single, peaking at #91 on the U.S. Billboard Hot 100 in May 1986.
Many of Byrne's mannerisms, such as the physical spasms, unfocused eye movements, and sharp intakes of breath, were inspired by his choreographer Toni Basil.
The sporadic dancing David Byrne does in the video was actually choreographed by Toni Basil. You may remember her by the 1982 song "Mickey".
"Once in a Lifetime" is a song released in 1981 as the first single from fourth studio album, 1980's Remain in Light.
It was named one of the 100 most important American musical works of the 20th century by National Public Radio.