Lyrically, the song talks about sexual desire, though it has been argued that it's actually about a young man coming to terms with his homosexuality.
Music critics hailed it as one of Madonna's strongest disco inspired tracks and complimented its refreshing dance oriented nature.
It was commercially successful; peaking at number seven on the Billboard Hot 100 and reaching the top ten in several countries including Canada, New Zealand, and the United Kingdom, while topping the charts in Italy.
The accompanying music video for "Deeper and Deeper" was directed by Bobby Woods.
Madonna has performed "Deeper and Deeper" in three of her concert tours; the last being the Rebel Heart Tour (2015-16).