The song was inspired by the group's interest in American music.
It is the second track from band's 1987 album The Joshua Tree and was released as the album's second single in May 1987.
The song was a hit, becoming the band's second consecutive number-one single on the US Billboard Hot 100 while peaking at number six on the UK Singles Chart.
"I Still Haven't Found What I'm Looking For" exhibits influences from gospel music and its lyrics describe spiritual yearning.
Lead singer Bono's vocals are in high register and lead guitarist the Edge plays a chiming arpeggio.