Most vintage Rudy Ray Moore movie scenes are recreated in their entirety with modern actors. However, in the house escape scene ("Bitch, are you for real?!") from The Human Tornado (1976), only the close-up shots of Moore were replaced, so Eddie Murphy appears to interact with the original supporting cast.
D'Urville Martin really appeared in Rosemary's Baby (1968). He played an elevator operator, the only African-American character. He appeared in two scenes, with one on-camera line of dialogue.
Keegan-Michael Key was a huge fan of Rudy Ray Moore before getting cast in this film. While working on The Predator (2018), the other cast members would come to his trailer to watch Moore's films.
When Jerry Jones and Rudy Ray Moore are starting to write the script for Dolemite (1975), Moore starts running down a laundry list of what he wants to put in the film (from kung-fu fights to an exorcism). When Jones gets exasperated and questions the exorcism scene, Moore realizes that he has gone "too far" with his ideas, and suggests "putting the devil in another movie." This is an inside reference to the future Moore film Petey Wheatstraw (1977).
Although the film is about the making of Dolemite (1975), Rudy Ray Moore's first film, numerous Easter eggs reference Moore's later movies. The police car chase, Dolemite fleeing the house ("Bitch, are you for real?!"), the exploding car, and the sex scene are from The Human Tornado (1976). Moore repeatedly saying ,"Put your weight on it!", and the main character in the play vowing to take revenge against a drug dealer, are references to Disco Godfather (1979).