Released on May 17, 1946 as part of a double bill with The Cat Creeps (1946). Universal Pictures, unlike most major studios, lacked a proprietary theater chain and often sold it's B-picture horror/mystery pictures as double bills, making weak pictures more attractive and economical for independent theaters to advertise.
Largely shot on Universal's old "Hacienda" set, used on many of the studio's "B" westerns.
The film was shot between December 8-21, 1945 but retakes required several members of the cast, including June Lockhart and Don Porter to work through Christmas eve.
Dennis Hoey had been cast as Inspector Lestrade in several "Sherlock Holmes" movies when he made "She-Wolf of London."
Joan Wells was cast in the role of June Lockhart's character as a child because of her close resemblance to Lockhart, especially the shape of her nose so closely resembling Lockhart's.