The only Francis the Talking Mule movie to credit Chill Wills. This is due to his on-screen appearance as General Benjamin Kaye instead of his usual voiceover duties as Francis.
Mamie Van Doren said she didn't want to be in the film but she was contracted to Universal and had to do it. Clint Eastwood was a friend of hers and when he found out she was in it, he asked her to help him get a part. She told him "God, why are you trying to get into that movie? I'm trying to get out of it." She said the only reason anyone starred in them was because they were forced to do it. Eastwood would appear in the next movie in the series, Francis in the Navy (1955).