(at around 44 mins) Joe enters a bar under the Third Avenue El. The building number is 915, and the writing on the front window is "Clarke's Cafe". That's none other than P.J. Clarke's at 915 Third Ave., which is still there and barely changed.
The address given for Lorrison - 170 Central Park West - is that of the New York Historical Society.
This film was a failure at the box office for MGM, resulting in a loss of $467,000 ($5.45M in 2022) according to studio records.
The drugstore that Joe Norson calls from is the set of another MGM film noir, Tension (1949), which was shooting at approximately the same time.
Trinity Church, the parish church of the Wall Street financial district, is featured as Joe's wife runs to him at the film's end. It is likely that the chase scene was filmed early on a weekend morning in that area, as at the time, the district was largely deserted outside of the work week.