Professor Danforth's cartoon machine was based on a real technique being developed by producer Norman Maurer. It involved filming live action actors in special high contrast makeup and costumes and using special processing techniques to create cartoon like images without the expensive labor intensive hand drawn process. The process never succeeded and the animated footage, and the Three Stooges cartoon series were created using traditional techniques.
Actors George N. Neise and Rayford Barnes, who play the Martians Ogg and Zogg, can be seen without the heavy Martian makeup as the airline pilot and co-pilot.
The first 20 minutes is actually reused footage from an unsold television pilot called The Three Stooges Scrapbook (1963). The original pilot contained a laugh track and was filmed in color.
At least one scene of the Martian's attack (a building being blasted) is from Earth vs. the Flying Saucers (1956).
The shot of the flying saucers and some of the destruction scenes are from Earth vs. the Flying Saucers (1956) which Columbia had released six years earlier.