In one episode, Sister Bertrille is looking at home movies of herself from when she was a teenager. The home movies were actually footage from Sally Field's previous series, Gidget (1965).
Sally Field has admitted that she disliked the scripts so much that she refused to read them. She would learn her lines right before shooting each scene by looking at the script supervisor's script.
This is the first and only American television series to be set in Puerto Rico.
Sister Bertrille comes from a family of doctors. She is the only member of her family not to go into medicine.
In her 2004 interview with the Archive of American Television, Sally Field admitted she had little affection for either the series or her role as Sister Bertrille. "I always certainly tried to do my best with it but deeply didn't want to do it. It went for three years. It was hugely important time in my life, because I learned a lot, because I didn't want to do it, and because I hated it every day. I hated the garbage. I felt it was just trivia that I had to say. With Gidget (1965), there was some kernel of something real in it. It was the father-daughter relationship that I always could hang on. But there was nothing in the nun that I could make sense out of. It made no sense to me. It was just drivel. And people when they hear me talk like that, they get very angry, 'Oh, I grew up with that! I loved it.' Well, God bless gesund that you loved it, but it was drivel and nonsense. There wasn't any piece of it that had any human behavior in it. And that bothered me." She continued, "Madeleine Sherwood, who played Mother Superior, recognized my depression and how difficult this was for me and she recognized why, and she took me to the Actor's Studio. I didn't know that's where I needed to be, and it came a huge turning point in my life."