Wesley Snipes' character is mistaken for Arsenio Hall. In an episode of Martial Law (1998), Arsenio's character is mistaken for Wesley, and the woman who does so says "I loved you in 'Passenger 57!' "
After a streak of hits with Warner Bros. at the start of his career, 'Passenger 57' was one of two 1992 releases that were offered to Steven Seagal by the studio. He could only do one, since both films were being shot simultaneously. He chose 'Under Siege' instead.
Partially filmed in Central Florida, Wesley Snipes spoke at his former Orlando high school (Jones High) offering paid roles as extras to students with high grade point averages. The students that met this requirement were placed on a list and randomly selected from that list and can be seen portraying attendees in a carnival scene as John Cutter searches the crowd in pursuit of the terrorists.
This was originally a vehicle for Sylvester Stallone but he turned it down. However, just for fun, the script writer named one of the major characters, "Sly".
There were no stunt doubles used for the final fight between Cutter and Rane. Wesley Snipes and Bruce Payne insisted on doing the scene themselves despite the protests of the producers, but director Kevin Hooks insisted, as well.