Screenwriter Daniel Pyne once rented an apartment to a tenant that he could not evict. The film was inspired by this scenario.
Some law professors have referenced and/or shown this movie in class to demonstrate tenant rights.
The home of Melanie Griffith and Matthew Modine's characters is not in Pacific Heights at all, but right across town in San Francisco's Potrero Hill district at the corner of Texas Street and 19th Street.
Christopher Reeve unsuccessfully lobbied John Schlesinger personally for the "Carter Hayes" role.
Beverly D'Angelo was uncredited in her role as Ann Miller, the girlfriend of Carter Hayes (Michael Keaton).