At some point Nurses was viewed by more people than it's parent series "Empty Nest" was viewed by.
During a commercial break of Nurses in 1991 the first condom commercial on network television aired.
There are some subjects that are sometimes considered 'taboo' to talk about, that are made mentionable in this series. For example the possibility of hospitals in existence that are driven to make profit instead of making people healthy.
The hospital as seen in external lead-in shots was in real-life Hoag Hospital in Newport Beach, California. The same hospital was used in "Empty Nest", the show which "Nurses" originated from.
Currently the series is the most popular in the country of the Netherlands which last aired the series in 2005. The United States of America take the second place.