In 1995, Charlize Theron was newly arrived in Hollywood after stints as a model and a dancer, living in a fleabag motel, and running out of money. Her mother had sent the twenty-year-old Theron a check from South Africa, but when she went to the bank to cash it, they refused her. Fed up, Theron threw what has been repeatedly called "a tantrum." That argument, coupled with her beauty, caught the eye of an agent, who promptly handed over his business card. Fast-forward a few months later, and Theron, in white lingerie, towered over Los Angeles in billboards for 2 Days in the Valley.
Charlize Theron did not know how to properly film a fight scene and ended up really punching Teri Hatcher in the face by accident. She apologized by buying her some cheap beer.
Paul Mazursky's character has an Emmy Award in his apartment; Mazursky himself was nominated for two Emmys for his writing achievements on The Danny Kaye Show (1963).
Composer Jerry Goldsmith wrote a score for this film that wasn't used. In June, 2012, Intrada Records released Goldsmith's score on a limited edition run on CD (the replacement score was not included). It was later discontinued.