- Bob Balaban(segment "5: 24, The")
- Patricia Benoit(segment "Fern's Heart of Darkness")
- Julie Dash(segment "Sax Cantor Riff")
- Jonathan Demme(segment "Subway Car from Hell")
- Abel Ferrara(segment "Love on the A Train")
- Alison Maclean(segment "Honey-Getter")
- Craig McKay(segment "Red Shoes, The")
- Lucas Platt(segment "Underground")
- Seth Zvi Rosenfeld(segment "Listeners, The") (as Seth Rosenfeld)
- Adam Brooks(segment "Subway Car from Hell")
- John Guare(segment "The Red Shoes")
- Lynn Grossman(segment "The 5: 24")
- Angela Todd(segment "Fern's Heart of Darkness")
- Seth Zvi Rosenfeld(segment "The Listeners") (as Seth Rosenfeld)
- Albert Innaurato(segment "Underground")
- Danny Hoch(segment "Honey-Getter")
- Julie Dash(segment "Sax Cantor Riff")
- Marla Hanson(segment "Love on the A Train")
- Rosie Perezcreator
- Bill Irwin(segment "Subway Car from Hell")
- Tina North(segment "Subway Car from Hell")
- Paul Lazar(segment "Subway Car from Hell")
- Andre B. Blake(segment "Subway Car from Hell")
- Anthony S. Calypso(segment "Subway Car from Hell")
- Robert W. Castle(segment "Subway Car from Hell")
- Marlon Cherry(segment "Subway Car from Hell")
- Carl J. Ferrazza(segment "Subway Car from Hell")
- Daniel Freedman(segment "Subway Car from Hell")
- Marc Mueller(segment "Subway Car from Hell")
- Paul Mueller(segment "Subway Car from Hell")
- Simon Seven(segment "Subway Car from Hell")
- Joe Toutebon(segment "Subway Car from Hell") (as Joseph Toutebon)
- Daniel Wolff(segment "Subway Car from Hell")
- Mari Danzi(segment "Subway Car from Hell")
- Lara McFarlane(segment "Subway Car from Hell")
- Angie Utt(segment "Subway Car from Hell")
- Audrey Meyers(segment "Subway Car from Hell")
- Denis Leary(segment "The Red Shoes")
- Christine Lahti(segment "The Red Shoes")
- N'Bushe Wright(segment "The Red Shoes")
- Kevin Corrigan(segment "The Red Shoes")
- Marie Barrientos(segment "The Red Shoes")
- O.L. Duke(segment "The Red Shoes")
- Ellen Gould(segment "The Red Shoes")
- John C. Vennema(segment "The Red Shoes")
- Sixto Ramos(segment "The Red Shoes")
- Erika Greene(segment "The Red Shoes")
- Steve Zahn(segment "The 5:24")
- Jerry Stiller(segment "The 5:24")
- Bonnie Hunt(segment "Fern's Heart of Darkness")
- Richard Spore(segment "Fern's Heart of Darkness")
- Mekhi Phifer(segment "Fern's Heart of Darkness")
- José Ramón Rosario(segment "Fern's Heart of Darkness")
- Nancy Ticotin(segment "Fern's Heart of Darkness")
- John Ford Noonan(segment "Fern's Heart of Darkness")
- Lili Taylor(segment "The Listeners")
- Michael Rapaport(segment "The Listeners")
- Israel Horovitz(segment "The Listeners")
- Mercedes Ruehl(segment "Underground")
- Zachary Taylor(segment "Underground")
- Peter Sarsgaard(segment "Underground") (as Peter Scarsgaard)
- Jeremy Jordan(segment "Underground")
- Bruce Smolanoff(segment "Underground")
- Rob Clasen(segment "Underground")
- Jay Bailey(segment "Underground")
- Sarita Choudhury(segment "Honey-Getter")
- Nicole Ari Parker(segment "Honey-Getter")
- Ajay Naidu(segment "Honey-Getter")
- Danny Hoch(segment "Honey-Getter")
- Steven Randazzo(segment "Honey-Getter")
- Gi Shen(segment "Honey-Getter")
- Kenny Garrett(segment "Sax Cantor Riff")
- Sam Rockwell(segment "Sax Cantor Riff")
- Sol Frieder(segment "Sax Cantor Riff")
- Tammi Cubilette(segment "Sax Cantor Riff")
- Kavi Ramachandran(segment "Sax Cantor Riff") (as Kavitha Ramachandran)
- Bruklin Harris(segment "Sax Cantor Riff")
- Taral Hicks(segment "Sax Cantor Riff")
- Daniel Rous(segment "Sax Cantor Riff") (as Dan Rous)
- Will Hare(segment "Sax Cantor Riff")
- Rosie Perez(segment "Love on the A Train")
- Michael McGlone(segment "Love on the A Train") (as Mike McGlone)
- Gretchen Mol(segment "Love on the A Train")
- Gregory Hines(segment "Manhattan Miracle")
- Anne Heche(segment "Manhattan Miracle")
- George T. Odom(segment "Manhattan Miracle") (as George Odom)
Rest of cast listed alphabetically
- John D. Bair(uncredited)
- John Bryant(uncredited)
- Christopher Del Gaudio(segment "Subway Car from Hell") (uncredited)
- Mark Robert Gordon(segment "Underground") (uncredited)
- Stacie Johnsen(uncredited)
- Adrian Lee(uncredited)
- Bonnie Monaghan(uncredited)
- Steve Nuke(segment "Love on the A Train") (uncredited)
- Frank Turek(segment "Subway Car from Hell") (uncredited)
- Chris White(uncredited)
- Jonathan Demmeexecutive producer
- Richard Guayproducer
- Rosie Perezexecutive producer
- Edward Saxonexecutive producer
- Valerie Thomasproducer
- Victoria Westheadassociate producer
- Tom Hurwitz(segment "Red Shoes, The")
- Tony C. Jannelli(segment "Subway Car from Hell") (as Anthony Jannelli)
- Ken Kelsch7 of 10 segments
- Adam Kimmel(segment "Manhattan Miracle")
- Angelo Corrao(segment "5: 24, The") (as Angelo Correo)
- Elizabeth Kling(segments "Fern's Heart of Darkness", "Sax Cantor Riff", "Love on the A Train")
- Colleen Sharp(segment "Red Shoes, The")
- Donna Stern(segment "Listeners, The")
- Jeffrey Wolf(segments "Underground", "Honey-Getter", "Manhattan Miracle")
- Dionne Alexanderhair stylist: Ms. Perez
- Daisy Curbeonadditional hair stylist / key hair stylist
- Annie M. DeMillekey hair stylist (as Annie de Mille)
- Bella Sirugoadditional makeup artist
- Victor De Jesusproduction supervisor
- Eitan Hakamipost-production supervisor
- Victoria Westheadunit production manager
- Steve Boothsecond second assistant director (as Stephen Booth)
- Lisa Janowskisecond assistant director
- Todd Pfeifferfirst assistant director (as Todd R. Pfeiffer)
- Jonathan Starchfirst assistant director
- Victor Littlejohnkey on-set dresser
- Ben Telfordassistant art director
- Mark Bachmansign designer (uncredited)
- Carlos Menéndezassistant art director (uncredited)
- Evan T. Chenassistant sound editor
- Lewis Goldsteinsupervising sound editor
- Glenfield Paynesound effects editor
- Joe Romanosound mixer
- William Sarokinsound mixer
- Reilly Steelere-recording mixer
- Allan Zaleskiassistant sound editor
- Dustin DuPilkaassistant foley artist (uncredited)
- Jay Carradostunt double: Wayne
- Bill Almeidaelectrician
- Brian Carmichaelvideo assist operator
- Shaun Gilbertelectrician
- Robert Kummertkey grip
- Dennis A. Liveseyfirst assistant camera
- Jamie A. Marlowecamera loader
- Don Muchowgaffer
- Mark Schwentnerbest boy electric
- Lynne Maureen Curtiswardrobe supervisor
- Michelle Martiniassistant costume designer
- Molly Bernsteinassociate editor
- Jason Blockpost-production assistant
- Keith Croketassistant editor (segment "The Red Shoes")
- Michelle Harrisonassistant editor
- Lara Khachooniassistant supervising editor
- Dwayne Alexander Smithlocation assistant (as Dwayne A. Smith)
- Al Valentinelocation manager
- Mecca Bodegamusician
- Tod Holcombmusic editor
- Alex Steyermarkmusic supervisor / Score Producer
- Kent McGrewcolor timer
- Andrea F. Cannistraciproduction legal
- Luis A. Colonproduction assistant
- Nicholas Corraoproduction assistant
- Brian Judeoffice production assistant
- Keegan Martinproduction assistant
- Exile Ramirezproduction assistant
- Dawn Murphy Rileyproduction coordinator
- Sammy Verniproduction intern
- M.J. Magbanuaassistant production coordinator (uncredited)
- Liz Dykhousepost production accountant
- Margo Myersproduction accountant
- Albertine Andersonspecial events coordinator: MTA
- Neda Armianassistant: Jonathan Demme
- Marcus Bookspecial events coordinator: MTA
- Alan Grabelskyvice president production
- Miura Kiteassistant to producer (as Miura Smith)
- Mary Toblerassistant to producer
- Holly Watsonassistant: Richard Guay
- John D. Genoveseassistant to production executive (uncredited)
- Kenneth Uttdedicated to Kenny Utt
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