First talk show appearance for Jay Leno, when he was 21 years old.
The show started 1961 in Cleveland, when Westinghouse owned Channel 3 and called it KYW. When Westinghouse won a court case against NBC in 1965, they opted to own Philadelphia's Channel 3, taking "KYW" call letters and The Mike Douglas Show with them. New studios for the show were on Walnut Street, but moved to KYW headquarters at 5th and Market Streets near Independence Hall. Moved in 1978 to Los Angeles.