Mari Morrow, who plays Nikki's best friend Desiree, disappears midway through the first season. Producers felt the chemistry would be better if a heavier actress portrayed her best friend. Yvette Wilson later replaced her.
This was the number one most watched sitcom in Black American households for all five seasons.
A photo of Mo'Nique's real-life mother is visible on the living room table in every episode.
Countess Vaughn was pregnant throughout most of the fourth season. Because of this, showrunners wrote out Kim for the first few episodes of season 5.
Countess Vaughn had to wear a wig during the first season episodes because the producers did not like her "alternative haircut."