There seems to be quite a few comments on how bad this movie is.
I can see how it won't appeal to a younger (people younger than 30's) audience who may feel that the "occasional" straying from your girl/guy is okay and understandable, so what's the big deal?
I agree that the movie is slow and nothing much (or meaningful) happens until the "famous" ending. After watching it for about half an hour, I turned my attention to other things (computer, etc.) and didn't get back to the movie until at the ending. I picked it up again where Reno leaves for his out-of-town trip, and watched through to the end. I must say the ending disturbed me a lot - that is it made me really really sad. Reno and Holly had a potentially very good relationship, and obviously loved each other a lot (This shows even at the end when Holly was watching Reno being interviewed on TV in a bar - oh she was so sad) This ending raises a deeply philosophical question: Can one partner trust another after such an act? Even though I don't have a partner, I wondered after watching the movie how I would react if I were in Reno's shoes! Can one give up a potentially beautiful yet perhaps unlikely to be long-lasting relationship (one who strays once likely may stray again)? This movie failed because the producer did not know what audience he/she wants to, and therefore, target. It is - as some reviewers have said - not a comedy (particularly the ending). It does however - also as some reviewers said - have some funny moments. It has no nudity to attract male audiences, at least what I'd call nudity anyway. And certainly no "actions" - but then it is not intended to be an action movie.
I only gave it a 7 because of the "deep" ending - as much as it left a big lump in my throat for a long time....
