Daryl Gates and Tammy Dargan, the creators of the game, appear in it: Daryl F. Gates as the police chief, and Tammy Dargan as the unconscious woman in the theatre. Several more of the actors are employees of Sierra On-Line: Dana Dean, animator; Barry T. Smith, animator and writer; Rod Fung, cinematographer; Neal Grandstaf, music.
Due to game bug in the diskette version, the final score of points is not shown. It was fixed in the CD version. However, unlike most Sierra games, the maximum score of points does not appear in either version - so at the end, the player has no way of knowing whether achieved the full score or missed any point-awarding action.
George Esparza and Roger Griffith played also in the previous game Police Quest III: The Kindred (1991).
The killer in the game is believed to be based on the serial murderer Jeffrey Dahmer, who used to keep body parts from his victims inside his house.
If Carey keeps talking to the man at the check-in window of the impound lot, he mentions various TV shows, mostly police dramas: Beavis and Butt-Head (1993), Hawaii Five-O (1968), Columbo (1971), Kojak (1973), Dragnet (1951), Baretta (1975), Mod Squad (1968), MacGyver (1985) and Adam-12 (1968).