When Meg decides that she must be the one to go back to get Charles Wallace, her hair is pulled back into a loop bun with only a few hairs loose (at 01:40:41 as she speaks with her father). In one of the shots in the same scene, it is still a loop bun, but there's a considerable amount of hair that is out (at 01:40:58 after her Emily Dickinson quote), and then in the shot right after that, it's back to being neat with only a few hairs out.
(at around 9 mins) At the beginning of the movie when Meg and the schoolboys get into a semi-fight, the black boy is behind Meg when they're mocking her and then appears next to her in the next shot when the fight starts without time for him to have moved.
When Mrs. Whatsit says (at around 18 mins), "if this insect wanted to travel across my left hand to my right hand..." the insect is actually sitting in her right hand, pointing towards her left hand.