When Ray Liotta was asked why he decided to voice the main character of the game, he said: "for the money". Tommy Vercetti was meant to have a (voice only) cameo in Grand Theft Auto: San Andreas (2004), but since Ray Liotta was under the impression he was underpaid for this game, so he refused to return. In 2008, Sam Houser noted it was not that he was underpaid, but instead thinking he should've asked extra because of the game's later foundation success, to which Houser found considerably unsettling.
With the 100% completion of the game the player will get: 200 Health, 200 Armor, all vehicles can take double damage, a T-shirt that says "I completed Vice City and all I got was this lousy T-shirt", infinite ammo on all weapons, and sometimes there will be three body guards sitting inside the Vercetti Estate, and if you step into the pink markers, you will pay $1,000 for each bodyguard to follow you around.
The missions "No Escape" and "Cop Land", are references to No Escape (1994) and Cop Land (1997). Movies that stars Ray Liotta (Tommy Vercetti voice actor).
As of March 2004, this game was the best selling video game ever on a worldwide basis. The previous record holder was its predecessor: Grand Theft Auto III (2001). The record would later be beaten by it's successor: Grand Theft Auto: San Andreas (2004).
When switching radio stations you can hear pieces from Grand Theft Auto III (2001) radio stations hidden in the radio seek noise.