A full-scale model of the Texas was built for the film. After the 1865 sequence was filmed, it was dismantled and reassembled in Morocco.
Penélope Cruz initially thought she was too young to play a World Health Organization doctor. A real WHO doctor told her that doctors that go to dangerous locations are more likely to be young.
The interior of Massarde's toxic waste disposal plant was the factory in Britain where the jet engines for the Concorde were tested.
The camel wrangler, the only person able to jump from a camel onto a moving train, doubled for all the actors.
Because of footprints left in the sand, many of the desert shots had to be done in one take.