Among the celebrities and political figures usually spoofed in this series are Mel Tiangco, Mike Enriquez, Pia Guanio, Boy Abunda and President Gloria Macapagal-Arroyo.
Considered as the Filipino equivalent to Saturday Night Live (1975), as both shows have parody skits, and both air on weekends (athough the Philippine airing of Bubble Gang precedes one American airing Saturday Night Live by a day).
Michael V.'s two music video segments were inspired by Weird Al Yankovic's parody of hit songs. The segments - Myusik Tagalog Bersyon (MTB) and Music English Version (MEV) - further boosted the rating.
The segment, Ang Dating Doon. launched in 1998 was a spoof to the religious program, Ang Dating Daan. They originally intended to quote the Bible, but because of religious sensitivities, they just decided to quote English fairy tales and Tagalog nursery rhymes and make fun of it. It used the soundtrack from Voltes Five (Voltes Five (1977)) as music theme.
The show changed its jingle three times so far. The first jingle was a rock ditty entitled "Bubble Gang (Just Chew It!)", which figured prominently in the show's opening billboard (OBB) from 1995-1997. The second jingle was a reggae, "Chew (The Bubble Gang Ye!)" which had two versions. The first version played in the show's OBB from 1997-1999 while the second version (which was played from 1999-2002) removed the reggae beat and changed it into an a cappela performed by Michael V. and Ogie Alcasid. The current jingle, "Bubble Gang (Pwede!)" was adapted from the Mexican song "La Cucaracha". A second version of the jingle, a candy factory-like sound, is used in the "Bubble Gang" OBB until October 20, 2006.Today's OBB was a third and current version of "Bubble Gang (Pwede!)" with a little bit of tune from the first version, the vocals also returned and a little bit of new tunes also added. All the show's past and present jingles were made by Ogie Alcasid and Michael V.
Antonio Aquitania was the one responsible for creating Bubble Gang's hit spoof group Sexballs, which copied the antics of the SexBomb Dancers. Sexballs has also guested as a group in other GMA shows and appeared occasionally in concerts headlined by either Michael V. or Ogie Alcasid.