Widely regarded by a huge number of fans as the worst Transformers cartoon ever to be made, due to its crude and primitive computer-generated animation, inconsistent writing and shallow characters, error-laden dubbing, and the fact that the story stops halfway through, then goes on to repeat itself. Some think the reason for this is that a regular Japanese anime show is "required" to have 52 episodes (one for each week in a year), and the writers couldn't figure out a better way to meet that quota.
Whenever the characters needed to emote, surprisingly well drawn, high quality cel animation was used instead of the usual CGI animation. This is because the primitive CGI models were very stiff and were unable to feature any facial expression besides "closed mouth", "open mouth" and "wide open mouth". This technique was also used to animate the transformation sequences of the combiner teams.
Galvatron, Starscream, Cyclone, Demolisher and Tidal Wave all suffer terrible fates in one way or another.
The facial structure of the Autobot veteran Bulkhead, with his goggles and prominent mustache, was based on Paul Teutul Sr. from American Chopper: The Series (2002), according to the toy designers.
Unicron only says one line of dialogue in his own voice ("Unicron, transform!") in the entire series, in episode 43, 'Distribution'.