According to Louis C.K., the series had better ratings than Deadwood (2004), but a certain HBO executive hated the show and pushed for it to be cancelled. The executive felt that the show's working class image did not fit with the network's high class image.
Ellen was originally supposed to be a recurring character but C.K. enjoyed Kim Hawthorne's work so much that he made her a cast member. Because she was hired as a recurring character, she did not have a contract with HBO. During pre-production on the second season, Hawthorne wanted to leave the series to work on a pilot. C.K. convinced HBO to pay Hawthorne for the entire second season to keep her. The second season was never produced.
According to C.K., the sparse apartment set and the banter between Louie and Kim was inspired by The Honeymooners (1955). C.K. used the actual blueprints of The Honeymooners set when having his set built.
The first HBO sitcom to be taped before a live audience.
Pamela Adlon, the actress who plays Louis C.K.'s wife in Lucky Louie, also stars as a recurring love interest for Louis C.K.'s character in several episodes of the more recent TV series, Louie.