Corey Padnos replaced Jonathan Lipnicki as the role of George due to the latter's older age, while Kevin Schon and Rino Romano replaced Nathan Lane and Steven Zahn as Snowbell and Monty for unknown reasons.
This is the only Stuart Little movie rated G. The other movies were PG.
As of 2022, this is Michael J. Fox's last starring role in a feature film. His last live-action movie would be See You Yesterday (2019).
The animation style in this film is cel-shaded CGI, that closely represents the illustrations of E.B. White's original "Stuart Little" book.
Stuart Little 3 is the only film to have the instrumental version of Reeko's funk in this Croatian version.