Itty Bitty Titty Committee was the first feature film to be produced by the Professional Organization of Women in Entertainment Reaching Up (POWER UP), a non-profit and production company dedicated to promoting the representation of gay women in entertainment.
In one sequence, Anna and Sadie go to a music/book store and check out a bunch of books, albums and magazines. The ones visible on-screen are as follows: Books: "Confessions of the Guerrilla Girls" by the Guerrilla Girls; "The Best Democracy Money Can Buy" by Greg Palast; "Pretty in Punk" by Lauraine Leblanc; "Backlash" by Susan Faludi; "How Wal-Mart is Destroying America..." by Bill Quinn; "The Power of Feminist Art" by Broude & Garrard; "Radical Feminism: A Documentary Reader" by Barbara Crow; "The New Our Bodies, Ourselves" by The Boston Women's Health Book Collective; "Emma" by Howard Zinn; "We Owe You Nothing" by Daniel Sinker; "The Beauty Myth" by Naomi Wolf; "Zines! Volume One" by V. Vale; "Grassroots" by Baumgardner, Richards & LaDuke; "The Radical Women Manifesto" by The Radical Women; "Angry Women" by Vale & Juno. Magazines: Ms., February/March 2001 ("Oh My God, I'm a Hardcore Feminist!" cover); Bitch, Spring 2002 (Sandra Tsing Loh cover); Venus, Summer 2005 (Sleater-Kinney cover). Albums: Gossip - Standing in the Way of Control; PJ Harvey - Rid of Me; The Queers - Punk Rock Confidential; Tiger Trap - Tiger Trap; Sleater-Kinney - The Hot Rock; Sleater-Kinney - Dig Me Out; Sleater-Kinney - All Hands on the Bad One; various artists - Otis' Opuses (Kill Rock Stars sampler). This sequence lasts for 30 seconds.
Melonie Diaz's first nude scene.
The character of Anna was originally intended to be a Jewish girl named Hannah, but this was changed after Melonie Diaz was cast in the role.
The protest activities carried on by the C(i)A are based on real-life feminist group the Guerrilla Girls. Director Jamie Babbit received permission from the Guerrilla Girls to use their slogans in the film.