This is the only appearance of Maggie Page. She was created as a possible love interest for Alfred but never used again.
Poison Ivy's alias as Daphne Demeter is a giveaway in Greek mythology, Daphne was a nymph who was turned into a laurel tree, and Demeter is the goddess of grain and the harvest.
Alfred's behavior after ingesting the Demetrite is a clue to its plant transformative effects; in particular, the way sunlight restores his strength is indicative of photosynthesis the process by which chlorophyll-bearing plants produce nourishment.
The climax of the episode was adapted into a stage in the Super Nintendo game The Adventures of Batman and Robin.
All of the employees of Poison Ivy's Eternal Youth Spa (Violet, Lily, Poison Ivy, and even Ivy's alias: Daphne) are named after plants.