William Russ guest stars as Patrick O'Casey, the first heart bypass patient for Dr. Mark Craig (William Daniels) at St. Eligius, in a flashback to 1975. Daniels and Russ would later co-star as neighbors George Feeny and Alan Matthews in Boy Meets World (1993) from 1993 to 2000.
This episode takes place in 1935, 1945, 1955, 1965, 1975 and 1986.
This is the only episode in which Dr. Westphall's late wife Maureen appears.
When Dr. Craig remarks upon the inefficient state of St. Eligius to Dr. Auschlander he references "Camp Runamuck." The scene is set in 1965 when Camp Runamuck (1965) would have been on the air originally.
Terence O'Casey was born in 1945.