Nicette Bruno has a cameo in the pilot as a mysterious woman named Cleide, who senses Marcos' supernatural ability. The character pays homage to Ivani Ribeiro (Cleide Freitas) creator and writer of the original O Profeta (1977).
Thiago Fragoso visited spiritualist centers and studied spiritualism to fit in his character Marcos.
Glauce Graieb portrayed Ruth in the original series. The actress is the sister of Nívea Maria who portrays her mother Lia in this version.
Walcyr Carrasco changed the story's contemporary setting from the original version to the 50s in this one after the positive feedback received from previous series, the similarly themed Soul Mate (2005).