John Cameron Mitchell was attracted by the script, and by the personal fact that at 14, he lost his 10-year-old brother to a heart problem; "It was a sudden, unexpected event. It defined a family forever and recovering from it was something we're still doing."
Miles Teller became good friends with Nicole Kidman and her husband Keith Urban during production. Following this, in 2016, Teller was once spontaneously invited to join Urban on stage during his show in New Mexico to duet on The Temptations' "My Girl". This marked Teller's first time singing for a live audience.
According to Aaron Eckhart, he attended a support group meeting for parents who had lost a child - in character. He told his character's story to the group and was consoled by the group's members.