Alexis Bledel is almost 6 years older than co-star Blake Lively. They are both aged 19 in the movie.
Bridget's college, Brown University, and Lena's college, Rhode Island School of Design, are on the same street in Providence, Rhode Island. The schools are right next to each other.
While filming in Santorini, Blake Lively stepped on a sea urchin and had "like, 42 needles stuck in her foot." They did not have any pain medicine, and the doctors had to pick them out of her foot one by one.
In a deleted scene, Carmen ineptly attempts to "interpret" between English- and Greek-speaking people by speaking only Spanish. This explains why in the next scene (which remains in the movie), Tibby says to Carmen, "Oh, so you speak Greek now?"