The film features archive recordings of William Hanna, who did all of the original screeches, yells, gasps, shrieks, howls, and screams for Tom and Jerry heard in the original cartoons from 1940 to 1958. It's the same technique used previously in The Peanuts Movie (2015), where all the Snoopy's screeches, yells, gasps, shrieks, howls, and screams were the made by Bill Melendez in the original cartoons from 1965 to 2006 (including movies, TV series and TV specials).
When Jerry is in his bathtub he is reading a book or magazine titled Secret Squirrel. Secret Squirrel was Hanna-Barbera cartoon that ran from 1965-66 featuring a James Bond-esque adventures.
This is the first Tom and Jerry theatrical film to be made without the original creators William Hanna and Joseph Barbera who died in 2001 and 2006, respectively.
The film is dedicated to veteran animator Gene Deitch (1924 - 2020), who worked on several "Tom & Jerry" features in his career.
The film contains gags from previous "Tom & Jerry" cartoons:
- the gag of Jerry socking Tom in the eye comes from Mouse Trouble (1944)
- the gag with the fishing line comes from Cat Fishin' (1947)
- Tom playing a piano comes from The Zoot Cat (1944).