When Alex, played by Justin Chambers, walks in on Meredith, played by Ellen Pompeo, and Cristina, played by Sandra Oh, lying in a hospital bed, you can briefly see that Ellen is pregnant with her daughter Stella.
First appearances of Jackson Avery and April Kepner.
The story line about Dr. Bailey's patient, Sarah Freemont, continues in Right Here, Right Now (2009).
It's revealed that Callie's father's name is Carlos.