When Howard (Marlon Wayans) is fighting a clown, he says, "Homey don't play that". This is a reference to Homey the Clown from In Living Color, who was played by Marlon's brother, Damon Wayans.
Marlon Wayans mentions Beyonce and Jay Z. Kelly Rowland was former Band member of Destinys Child including Beyonce.
For Halloween, Ramona is dressed as Cruella DeVille from 101 Dalmatians, Jamie is "Ghost Spider" Gwen Stacy with her hood down from Spider-Man comics, and Mario is Lin-Manuel Miranda as Hamilton.
Neighbor Sully (Rob Riggle) is dressed up as Rick Grimes from The Walking Dead.