During the first week of filming, Tom Holland broke his nose after getting punched in the face by a stuntman during a fight scene.
On the last day of filming, Tom Holland passed out on camera while performing a scene where he had to hold his breath under water.
Tom Holland lost out on the lead role in 1917 (2019) and missed the premiere of Avengers: Endgame (2019) due to reshoots on this film.
Tom Holland, notoriously boyish-looking for his actual mid-twenties age, was asked to grow as much facial hair as he could for his role. All he could muster was the thinnest of a "Guy Fawkes" that is barely even visible outside of close-up shots, and which took him five whole weeks to accomplish.
The studio pushed the release multiple times, ultimately offering the film very little marketing and a release in January of 2021, before most theaters re-opened from the Coronavirus Pandemic. This is about as much of a disservice to a film that a studio can do, and clearly showed they had little to no faith in the movie despite its stars and fans of the book series being abundant. Tom Holland expressed his disappointment in this, saying that the film was a labor of love and that everyone involved in the production worked really hard to make a good film.