Goofs

Knives do work better in close counters, but not when someone is pointing an automatic weapon to your back.

Spelling and punctuation errors in subtitles.

Incorrectly regarded as a goof: When Ashley is possessed and fires upon Mr. Kennedy, it seems like the gun clicks on an empty chamber. Actuality, the semi-automatic jammed (which occurs but not often). This is verified at the end of the cut-scene when Leon pulls back the slide to clear the jam and inspects the magazine, which has a round available.

The flaming statue in the clock tower doesn't set the wooden structures on fire.

At the bottom of the dungeon there are torches lit even though no one could have lit them.

The messages that Leon receives show a video, yet he cannot possibly see a video since he only has earphones.

Weapons and equipment are carried in a briefcase, but Mr. Kennedy isn't visibly carrying a briefcase.

Luis never said where his laboratory was located, or how to even use the machine. Even though the machine was turned on upon arrival, neither Leon or Ashley could have possibly known which buttons to push.

Luis Serra is a highly sophisticated individual, yet he told Leon his real name. In order to evade the US government from persecuting him, he should have used a fake name.

At the castle dock, Krause could have sabotaged the unused boat so that Mr. Kennedy couldn't follow him, but failed to do so.

Krauser made it very clear in a tape recording that he had an entire battlefield set up and that he wanted to challenge Leon based upon his skills. So it's obvious that he wanted Leon to follow him.