Actors Sebastian Stan and Dylan Baker also starred together in cancelled TV series, Kings (2009), where Stan also played a gay character.
The former United States Secretary of State Colin Powell's daughter, Linda Powell, guest stars in a couple episodes.
Sigourney Weaver and James Wolk worked together previously in the movie "You Again" (2010)
Carla Gugino and Sebastian Stan have worked in the Marvel Cinematic Universe and the DC Extended Universe respectively with Gugino appearing in Man of Steel (2013) and Batman v Superman: Dawn of Justice (2016) as Kryptonian ship voice Kelor and in a previous DC comics film Watchmen (2009) as Sally Jupiter / Silk Spectre while Stan appears as Bucky Barnes / Winter Soldier in the Captain America trilogy.
Would be Sebastian Stan's last time playing a gay character, as he did not want to be typecast constantly playing troubled gay men.