When asked about her attitude on performing nude in horror films, Erin P. Ryan said, "I really don't have a problem with it. The human body is the human body. I want the nudity that I do to make sense in a film. Now, if it's a B horror fun movie like Babysitter Massacre you're going to have the three B's blood, boobs, and beasts. It's just a staple. I have no problem doing that. I was proud. It was like, hey I'm in a B movie and I'm naked!"
According to Henrique Couto, this was the last independent film on DVD to be carried at Blockbuster.
Director Henrique Couto said he gets offended when reviews criticize the depth he gives female characters, because those characters eventually strip naked or take a shower. He said, "If a character is shown naked in the shower, is she automatically supposed to not have depth? When you rent or buy a movie called Babysitter Massacre, you almost have an expectation of what you're going to get. I wanted to deliver, but I knew that I could deliver and do a good job. It just blew my mind that the critics were only focusing on the fact that the actresses took off their clothes. Ultimately, though, we ended up with more positive feedback than we did negative."
Odette Despairr's first role. She was so excited to get the part she readily agreed to perform fully nude when the director asked. She said in an interview that she has never been shy so being stark naked on set in front of the crew while filming didn't bother her at all. In fact, she thinks they were more embarrassed than her. Between shots she didn't bother putting on a robe and wandered around nude. She figured everyone had seen her naked so why cover up? She thought it was hilarious when she'd chat with the crew guys and they'd try to avoid looking down at her body. One of her favorite horror actresses is Julie Strain and she had read that Strain used to do the same thing to tease the crew on her films.
Henrique Couto made this film as an homage to the 1980s direct-to-video slasher movies he loved where women are in their lingerie, naked, and in peril. He said he grew up renting those films even though he was far too young to be renting them.