Owen Garrison as an actor who played the Blue Falcon on an old, campy TV series, and is in conflict with a movie studio's darker version of Blue Falcon; the studio has also been preventing the original series from public view. This is a reference to the real life struggle that went on between Batman (1966) star Adam West and the makers of the Dark Knight trilogy.
The Blue Falcon actor Owen Garrison is named after the Blue Falcon's original voice actor Gary Owens, who also guest-starred in Legends of the Dark Knight (1998) as a "retro" version of Batman, a similar character. Although still active in 2012, Owens was not featured in this movie. His final performance as BF was in Johnny Makeover/Back on Shaq (2004).
Scooby-Doo removes his Dynomutt costume, and says "I'm Dynomutt no more." This is a reference to the Spider-Man comic "Spider-Man No More" when Peter Parker gave up being Spider-Man, dramatized as a subplot of Spider-Man 2 (2004).
The Sheldorf hotel is named after San Diego Comic-Con founder Shel Dorf. This film features a comic convention based on the Comic-Con.
Jennifer Severin is based on real life director Michael Bay during his involvement in the Transformers film series.