Trisha Cappelletti is voiced by a man because the actress who was supposed to voice her never showed up.
Saison Marguerite was initially going to be portrayed by a Bratz doll. The creators decided against it and ended up dressing the Saison doll in the outfit of the Bratz doll they intended to use.
Several memorable lines of dialogue, particularly insults such as Bridget Tice's "abortion" insult and Juliette Bonnet's "boom-boom cooter" insult, were improvised during recording.
Shay Van Buren is deaf in one ear as a result of being hit in the head with a Ryan Cabrera promotional hackie sack by Matthew Derringer in the third grade.
Mackenzie Zales, whom is currently voiced by Kate Frisbee, was originally voiced by Marian Bruno in the first two episodes in which Mackenzie appears.