Excluding sub series and crossovers, this is the 5th Mario game to be rated E10+ for Everyone 10 and up by the ESRB, after Mario Strikers Charged (2007), Mario & Luigi: Dream Team (2013), Super Mario Odyssey (2017) and Mario Strikers: Battle League (2022).
This is the first game to have Princess Peach as the starring role since Super Princess Peach (2005) 19 years prior.
Excluding sub series, this is the 2nd Mario game where Mario himself makes no appearance whatsoever, after New Super Luigi U (2013).