Viola Davis became the first African-American woman to receive an Emmy Award for Outstanding Lead Actress in a Drama Series because of her work on this show. She won in that category in 2015.
The iconic scene where Annalise Keating is wiping off her make up and removing her wig was Viola Davis's idea.
Alfred Enoch, who is British, spoke with his American accent for the Wes Gibbins character during the entirety of his time working on the show, both on and off set.
The title of every episode is part of the dialogue from the respective episode.
Viola Davis intentionally gave Annalise a heavy walk, as she didn't believe the character would walk well in heels.