After her house burned down and she had a mere $3 left in her bank account, Annie Murphy considered quitting acting altogether. Fortunately, she got the audition for "Schitt's Creek" and landed the role of Alexis.
Eugene Levy (Johnny) works on the show with his real-life son and daughter. Dan Levy plays David, Johnny's son, and Sarah Levy plays Twyla, a waitress at the town diner.
As of 2020, it holds the record for the most Emmy wins in a single season for a comedy series (winning nine). It is also the first comedy series to sweep the Primetime Emmy Awards in all four major acting categories in a single year. In 2004, Angels in America (2003) won all four major acting awards in the Limited Series category in the same year. In 2021, The Crown (2016) won all four major acting awards in the Drama Series category in the same year.
According to Annie Murphy, Eugene Levy was thrilled to work with his children. While off-screen, he would mouth their lines along with them.
Throughout the series, Moira refers to individual wigs in her extensive collection by women's names. Names used included Krista, Robin, Maureen, Lorna, and Cindy. During a June 2020 Variety interview, Catherine O'Hara said that if it falls on her to name the wigs, she uses friends' names. In the same interview, O'Hara said that she was the one who asked if her character could wear and change wigs often, inspired by a dinner party she once went to where, with no explanation, the hostess would excuse herself and return wearing a different wig every half-hour or so.