The black and white cat graphic shown in portions of the opening credits is Grumpy Cat's real life brother, Pokey.
Grumpy Cat is a female, and her name is Tardar Sauce.
The second Internet meme to be the basis for a movie, after Safety Not Guaranteed, which also starred Aubrey Plaza.
Chrystal, the main character played by Megan Charpentier, is named after Chrystal Bundesen -- the daughter of Grumpy Cat's real-life owners.
On "Jimmy Kimmel Live!", Aubrey Plaza stated the film did not make any sense to her and jokingly preferred to watch the film intoxicated.